Chloroform 99% for HPLC & Spectroscopy 2.5L

Chloroform 99% HPLC – Identification of Product Chemical Code: HPLC-C1 Chemical Name: Chloroform Chemical Grade: HPLC Chemical Formula: CHCl₃ Chemical Weight: 119,38 g/mol CAS No: 67-66-3 Chemical Synonyms: Trichloromethane Methylidyne Trichloride Chloroform 99% HPLC – Hazards Identification REACH No: No Data Available Signal Word: Danger Supplemental Hazard Information: Additional Hazard Information: This substance contains no components considered to be either persistent, bio-accumulative and toxic (PBT), or very persistent and very bio-accumulative (vPvB) at levels of 0.1% or higher. Chloroform 99% HPLC – Hazards statements H302 – Harmful if swallowed. H315 – Causes skin irritation. H319 – Causes serious eye irritation. H331 – Toxic if inhaled. H336 – May cause drowsiness or dizziness. H351 – Suspected of causing cancer. H361d – Suspected of damaging the unborn child. H372 – Causes damage to organs through prolonged or repeated exposure. Chloroform 99% HPLC – Precautionary statements P261 – Avoid breathing vapours. P281 – Use personal protective equipment as required. P305 P351 P338 – IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P311 – Call a POISON CENTER or doctor/ physician. Chloroform 99% HPLC – Composition of Chemical Chemical Formula: CHCl₃ EC No 1272/2008: No Data Available Chloroform 99% HPLC – First Aid Measures General Advice: Consult a physician. Show this safety data sheet to the doctor in attendance. If: Inhaled: If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. If: Skin Contact: Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician. If: Eye Contac: Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If: Swallowed: Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. Important Symptoms: The most important known symptoms and effects are described in the labeling section. Immediate Medical Attention: No Data Available Chloroform 99% HPLC – Firefighting Measures Extinguishing Media: Use Water spray, Alcohol-resistant foam, Dry chemical or Carbon Dioxide. Hazards Arising: Carbon Oxides, Hydrogen Chloride gas Advice for Firefighters: Wear self-contained breathing apparatus for firefighting if necessary. Info for Firefighting: No Data AvailableAccidental Release Measures Personal Precautions: Wear respiratory protection. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Enviromental Precautions: Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Method for Containment: Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed containers for disposal. Handling and Storage Personal Precautions: Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Enviromental Precautions: Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Storage class (TRGS 510): Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects Exposure Controls | Personal Protection Derived No Effect Level (DNEL) Workers | Application Area | Exposure Routes | Health Effect | Value No Data Available Consumers | Application Area | Exposure Routes | Health Effect | Value No Data Available Predicted No Effect Concentration (PNEC) No Data Available Engineering Controls: No Data Available Eye/Face Protection: Face shield and safety glasses. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin Protection: Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching gloves outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.Full contact – Material: Fluorinated rubber. Minimum layer thickness: 0,7 mm Break through time: 480 min. Material tested: Vitoject®. Splash contact – Material: Fluorinated rubber. Minimum layer thickness: 0,7 mm Break through time: 480 min. Material tested: Vitoject®. Data source: KCL GmbH, D-36124. Test method: EN374. If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection: Complete suit protecting against chemicals. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Respiratory Protection: Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multipurpose combination (US) or type AXBEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Physical and Chemical Properties Appearance: Colourless, highly refractive liquid Odour: Characteristic Odour Odour Threshold: No Data Available pH: No Data Available Melting Point: Melting point/range: -63 °C Boiling Point: 60,5 – 61,5 °C Flash Point: No Data Available Evaporation: No Data Available Flammability: No Data Available Upper/Lower Flammability or Explosive Limits: No Data Available Vapour pressure: 213,3 hPa ( 20,0 °C) Vapour density: No Data Available Relative density: 1,492 g/mL ( 25 °C) Water solubility: No Data Available Partition Coefficien: log Pow: 1,97Auto-ignition Temperature: No Data Available Decomposition Temperature: No Data Available Viscosity: No Data Available Explosive properties: No Data Available Oxidizing properties: No Data Available Other Safety Info: Surface tension: 27,1 mN/m ( 20,0 °C) Stability and Reactivity Reactivity: No Data Available Chemical Stability: Stable under recommended storage conditions. Possibility of hazardous reactions: No Data Available Conditions to Avoid: No Data Available Incompatible Materials: Strong oxidizing agents, Strong bases, Magnesium, Sodium/Sodium Oxides, Lithium Hazardous Decomposition Products: No Data Available Toxicological Information Acute Toxicity: LD50 Oral – Rat – 908 mg/kg Remarks: Behavioral: Change in motor activity (specific assay). Behavioral: Ataxia. Lungs, Thorax, or Respiration: Respiratory stimulation. LOEC Inhalation – Rat – male – 6 h – 500 ppm LD50 Dermal – Rabbit – > 20.000 mg/kg Skin Corrosion/Irritation: Rabbit Result: Irritating to skin. – 24 h Serious Eye damage | Eye Irritation: Rabbit Result: Irritating to eyes. – 24 h Cell Mutagenicity: Laboratory experiments have shown mutagenic effects. Carcinogenicity: Carcinogenicity – Rat – Oral Tumorigenic:Carcinogenic by RTECS criteria. Leukaemia The National Cancer Institute (NCI) has found clear evidence for carcinogenicity. Limited evidence of a carcinogenic effect. IARC: 2B – Group 2B: Possibly carcinogenic to humans (Chloroform) Reproductive toxicity: Suspected of damaging the unborn child. Suspected human reproductive toxicant Specific Target Organ Toxicity – Single Exposure: May cause drowsiness or dizziness. Specific Target Organ Toxicity – Repeated Exposure: The substance or mixture is classified as specific target organ toxicant, repeated exposure, category 1. – Liver, KidneyAspiration Hazard: No Data Available Ecological Information Ecological Toxicity: Toxicity to fish: LC50 – Leuciscus idus (Golden orfe) – 162 mg/l – 48 h, LC100 – Leuciscus idus (Golden orfe) – 220 mg/l – 48 h, LC50 – other fish – 97 mg/l – 96 h, LC50 – Danio rerio (zebra fish) – 121 mg/l – 96 h, NOEC – Oryzias latipes – 122 mg/l – 10 d, NOEC – Oncorhynchus mykiss (rainbow trout) – 24 mg/l – 96 h. Toxicity to daphnia and other aquatic invertebrates: EC50 – Daphnia magna (Water flea) – 79,00 mg/l – 24 h. Immobilization: EC50 – Daphnia magna (Water flea) – 51,6 mg/l – 48 h, NOEC – Daphnia magna (Water flea) – 120 mg/l – 11 d. Toxicity to algae: EC50 – No information available. – 500,00 mg/l – 24 h Ecological Persistence and degradability: No Data Available Bioaccumulative Potential: Bio-accumulation: Lepomis macrochirus (Bluegill) – 14 d – 0,11 mg/l Bio-concentration factor (BCF): 6 Mobility in Soil: No Data Available Results of PBT and vPvB Assessment: This substance contains no components considered to be either persistent, bio-accumulative and toxic (PBT), or very persistent and very bio-accumulative (vPvB) at levels of 0.1% or higher. Other Adverse Effect: Harmful to aquatic life. Disposal Considerations Waste Treatment Methods: Product Offer surplus and non-recyclable solutions to a licensed disposal company. Contaminated packaging – Dispose of as unused product. Transport Information UN Number: ADR/RID: 1888 IMDG: 1888 IATA: 1888 UN Shipping Hazard: ADR/RID: CHLOROFORMIMDG: CHLOROFORM IATA: Chloroform Transport Hazard Class: ADR/RID: 6.1 IMDG: 6.1 IATA: 6.1 Packaging Group: ADR/RID: III IMDG: III IATA: III Enviromental Hazards: ADR/RID: no IMDG Marine pollutant: no IATA: no Special Precautions: No Data Available Regulatory Information Safety, Health and environmental regulations: This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006. Chemical Safety Assessment: For this product a chemical safety assessment was not carried out. Additional Info: RTECS: FS9100000 Vomiting, Gastrointestinal disturbance. Exposure to and/or consumption of alcohol may increase toxic effects. To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. Disclaimer The information stated above is considered to be correct, but does not claim to be inclusive and shall only be used as a guideline. The information provided by this document is confirmed by our continuous updating of knowledge and adheres to the products appropriate safety precautions. It does not represent any guarantee of the product’s properties. RLS Chemicals and its Associates shall not be held accountable for any damage’s consequent of handling the above product