Congo red 25g

Congo red 25g – Identification of the substance Congo red (C.I. 22120) for microscopy 0322 It is not required to list the identified uses because the substance is not subject to registration according to REACH (< 1 t/a). Disodium-3,3′[[1,1-biphenyl]-4,4′- diyl(bis(azo)]bis(4-aminonaphthalin-1-sulfonate), Direct Red 28 1.2 Relevant identified uses of the substance or mixture and uses advised against Relevant identified uses: Laboratory chemical Laboratory and analytical use Uses advised against: Do not use for products which come into contact with foodstuffs. Do not use for private purposes (household). Safety data sheet SECTION 1: Identification of the substance/mixture and Company SECTION 2: Hazards identification 2.1 Classification of the substance or mixture Classification according to Regulation (EC) No 1272/2008 (CLP) Section Hazard class Category Hazard class and category Hazard statement 3.6 Carcinogenicity 1B Carc. 1B H350 3.7 Reproductive toxicity 2 Repr. 2 H361d For full text of abbreviations: see SECTION 16 2.2 Label elements Labelling according to Regulation (EC) No 1272/2008 (CLP) Signal word Danger Pictograms GHS08 Hazard statements H350 May cause cancer H361d Suspected of damaging the unborn child Precautionary statements Precautionary statements – prevention P202 Do not handle until all safety precautions have been read and understood Precautionary statements – response P308 P313 IF exposed or concerned: Get medical advice/attention For professional users only Labelling of packages where the contents do not exceed 125 ml Signal word: Danger Symbol(s) H350 May cause cancer. H361d Suspected of damaging the unborn child. P202 Do not handle until all safety precautions have been read and understood. P308 P313 IF exposed or concerned: Get medical advice/attention. Safety data sheet 2.3 Other hazards Results of PBT and vPvB assessment According to the results of its assessment, this substance is not a PBT or a vPvB. SECTION 3: Composition/information on ingredients 3.1 Substances Name of substance Congo red 25g Molecular formula C₃₂H₂₂N₆Na₂O₆S₂ Molar mass 696,7 g/mol CAS No 573-58-0 EC No 209-358-4 Index No 611-027-00-8 Substance of Very High Concern (SVHC) Name of substance CAS No EC No Listed in Remarks Congo red 573-58-0 209-358-4 Candidate list Carc. A57a Legend candidate list Substances meeting the criteria referred to in Article 57 and for eventual inclusion in Annex XIV Carc. A57a Carcinogenic (article 57a) SECTION 4: First aid measures 4.1 Description of first aid measures General notes Take off contaminated clothing. Following inhalation Provide fresh air. In all cases of doubt, or when symptoms persist, seek medical advice. Following skin contact Rinse skin with water/shower. Following eye contact Rinse cautiously with water for several minutes. In all cases of doubt, or when symptoms persist, seek medical advice. Following ingestion In case of accident or unwellness, seek medical advice immediately (show directions for use or safety data sheet if possible). 4.2 Most important symptoms and effects, both acute and delayed Fatigue, Varying degrees of pulmonary injury Safety data sheet 4.3 Indication of any immediate medical attention and special treatment needed none SECTION 5: Firefighting measures 5.1 Extinguishing media Suitable extinguishing media co-ordinate firefighting measures to the fire surroundings water, foam, alcohol resistant foam, dry extinguishing powder, ABC-powder Unsuitable extinguishing media water jet 5.2 Special hazards arising from the substance or mixture Combustible. Hazardous combustion products In case of fire may be liberated: Nitrogen oxides (NOx), Carbon monoxide (CO), Carbon dioxide (CO₂), Sulphur oxides (SOx) 5.3 Advice for firefighters In case of fire and/or explosion do not breathe fumes. Fight fire with normal precautions from a reasonable distance. Wear self-contained breathing apparatus. SECTION 6: Accidental release measures 6.1 Personal precautions, protective equipment and emergency procedures For non-emergency personnel Use personal protective equipment as required. Avoid contact with skin, eyes and clothes. Do not breathe dust. 6.2 Environmental precautions Keep away from drains, surface and ground water. 6.3 Methods and material for containment and cleaning up Advice on how to contain a spill Covering of drains. Take up mechanically. Advice on how to clean up a spill Take up mechanically. Control of dust. Other information relating to spills and releases Place in appropriate containers for disposal. Ventilate affected area. 6.4 Reference to other sections Hazardous combustion products: see section 5. Personal protective equipment: see section 8. Incompatible materials: see section 10. Disposal considerations: see section 13. Safety data sheet United Kingdom (en) Page 4 / 16 SECTION 7: Handling and storage 7.1 Precautions for safe handling Avoid exposure. Avoid dust formation. Measures to prevent fire as well as aerosol and dust generation Removal of dust deposits. Advice on general occupational hygiene Wash hands before breaks and after work. Keep away from food, drink and animal feedingstuffs. 7.2 Conditions for safe storage, including any incompatibilities Store in a dry place. Incompatible substances or mixtures Observe hints for combined storage. Protect against external exposure, such as UV-radiation/sunlight Consideration of other advice: Ventilation requirements Use local and general ventilation. Specific designs for storage rooms or vessels Recommended storage temperature: 15 – 25 °C 7.3 Specific end use(s) No information available. SECTION 8: Exposure controls/personal protection 8.1 Control parameters National limit values Occupational exposure limit values (Workplace Exposure Limits) Country Name of agent CAS No Identifier TWA[mg/m³] STEL[mg/m³] Ceiling-C[mg/m³] Notation Source GB dust WEL 10 i EH40/2005 GB dust WEL 4 r EH40/2005 Notation Ceiling-C Ceiling value is a limit value above which exposure should not occur i Inhalable fraction r Respirable fraction STEL Short-term exposure limit: a limit value above which exposure should not occur and which is related to a 15- minute period (unless otherwise specified) TWA Time-weighted average (long-term exposure limit): measured or calculated in relation to a reference period of 8 hours time-weighted average (unless otherwise specified) Safety data sheet Page 5 / 16 8.2 Exposure controls Individual protection measures (personal protective equipment) Eye/face protection Use safety goggle with side protection. Skin protection • hand protection Wear suitable gloves. Chemical protection gloves are suitable, which are tested according to EN 374. For special purposes, it is recommended to check the resistance to chemicals of the protective gloves mentioned above together with the supplier of these gloves. The times are approximate values from measurements at 22 ° C and permanent contact. Increased temperatures due to heated substances, body heat etc. and a reduction of the effective layer thickness by stretching can lead to a considerable reduction of the breakthrough time. If in doubt, contact manufacturer. At an approx. 1.5 times larger / smaller layer thickness, the respective breakthrough time is doubled / halved. The data apply only to the pure substance. When transferred to substance mixtures, they may only be considered as a guide. • type of material NBR (Nitrile rubber) • material thickness >0,11 mm • breakthrough times of the glove material >480 minutes (permeation: level 6) • other protection measures Take recovery periods for skin regeneration. Preventive skin protection (barrier creams/ointments) is recommended. Respiratory protection Respiratory protection necessary at: Dust formation. Particulate filter device (EN 143). P2 (filters at least 94 % of airborne particles, colour code: White). Environmental exposure controls Keep away from drains, surface and ground water. Safety data sheet SECTION 9: Physical and chemical properties 9.1 Information on basic physical and chemical properties Physical state solid Form powder Colour red brown Odour characteristic Melting point/freezing point 360 °C Boiling point or initial boiling point and boiling range not determined Flammability this material is combustible, but will not ignite readily Lower and upper explosion limit not determined Flash point not applicable Auto-ignition temperature not determined Decomposition temperature not relevant pH (value) 6,7 (in aqueous solution: 10 g/l, 20 °C) Kinematic viscosity not relevant Solubility(ies) Water solubility 25 g/l at 20 °C Partition coefficient Partition coefficient n-octanol/water (log value): 2,63 (calculated value) Vapour pressure not determined Density and/or relative density Density not determined Relative vapour density information on this property is not available Bulk density 600 – 700 kg/m³ Particle characteristics No data available. Other safety parameters Oxidising properties none 9.2 Other information Information with regard to physical hazard classes: hazard classes acc. to GHS (physical hazards): not relevant Safety data sheet United Kingdom (en) Page 7 / 16 Other safety characteristics: There is no additional information. SECTION 10: Stability and reactivity 10.1 Reactivity The product in the delivered form is not dust explosion capable; the enrichment of fine dust however leads to the danger of dust explosion. 10.2 Chemical stability The material is stable under normal ambient and anticipated storage and handling conditions of temperature and pressure. 10.3 Possibility of hazardous reactions Violent reaction with: strong oxidiser 10.4 Conditions to avoid UV-radiation/sunlight. 10.5 Incompatible materials There is no additional information. 10.6 Hazardous decomposition products Hazardous combustion products: see section 5. SECTION 11: Toxicological information 11.1 Information on hazard classes as defined in Regulation (EC) No 1272/2008 Classification according to GHS (1272/2008/EC, CLP) Acute toxicity Shall not be classified as acutely toxic. Acute toxicity Exposure route Endpoint Value Species Method Source oral LD50 15.200 mg/kg rat TOXNET Skin corrosion/irritation Shall not be classified as corrosive/irritant to skin. Serious eye damage/eye irritation Shall not be classified as seriously damaging to the eye or eye irritant. Respiratory or skin sensitisation Shall not be classified as a respiratory or skin sensitiser. Germ cell mutagenicity Shall not be classified as germ cell mutagenic. Carcinogenicity May cause cancer. Reproductive toxicity Suspected of damaging the unborn child. Safety data sheet Specific target organ toxicity – single exposure Shall not be classified as a specific target organ toxicant (single exposure). Specific target organ toxicity – repeated exposure Shall not be classified as a specific target organ toxicant (repeated exposure). Aspiration hazard Shall not be classified as presenting an aspiration hazard. Symptoms related to the physical, chemical and toxicological characteristics • If swallowed Data are not available. • If in eyes Data are not available. • If inhaled fatigue, varying degrees of pulmonary injury • If on skin Data are not available. • Other information none 11.2 Endocrine disrupting properties Not listed. 11.3 Information on other hazards There is no additional information. SECTION 12: Ecological information 12.1 Toxicity Shall not be classified as hazardous to the aquatic environment. . Aquatic toxicity (acute) Endpoint Value Species Source Exposure time LC50 560 mg/l rainbow trout (Oncorhynchus mykiss) ECHA 96 h Biodegradation Data are not available. 12.2 Process of degradability Theoretical Oxygen Demand with nitrification: 1,738 mg/mg Theoretical Oxygen Demand: 1,521 mg/mg Theoretical Carbon Dioxide: 2,021 mg/mg 12.3 Bioaccumulative potential Does not significantly accumulate in organisms. n-octanol/water (log KOW) 2,63 (Calculated value) Safety data sheet 12.4 Mobility in soil Data are not available. 12.5 Results of PBT and vPvB assessment Data are not available. 12.6 Endocrine disrupting properties Not listed. 12.7 Other adverse effects Data are not available. SECTION 13: Disposal considerations 13.1 Waste treatment methods This material and its container must be disposed of as hazardous waste. Dispose of contents/container in accordance with local/regional/national/international regulations. Sewage disposal-relevant information Do not empty into drains. 13.2 Relevant provisions relating to waste The allocation of waste identity numbers/waste descriptions must be carried out according to the EEC, specific to the industry and process. Waste catalogue ordinance (Germany). 13.3 Remarks Waste shall be separated into the categories that can be handled separately by the local or national waste management facilities. Please consider the relevant national or regional provisions. SECTION 14: Transport information 14.1 UN number or ID number not subject to transport regulations 14.2 UN proper shipping name not assigned 14.3 Transport hazard class(es) none 14.4 Packing group not assigned 14.5 Environmental hazards non-environmentally hazardous acc. to the dangerous goods regulations 14.6 Special precautions for user There is no additional information. 14.7 Maritime transport in bulk according to IMO instruments The cargo is not intended to be carried in bulk. 14.8 Information for each of the UN Model Regulations Transport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN) – Additional information Not subject to ADR, RID and ADN. Safety data sheet International Maritime Dangerous Goods Code (IMDG) – Additional information Not subject to IMDG. International Civil Aviation Organization (ICAO-IATA/DGR) – Additional information Not subject to ICAO-IATA. SECTION 15: Regulatory information 15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture Relevant provisions of the European Union (EU) Restrictions according to REACH, Annex XVII Dangerous substances with restrictions (REACH, Annex XVII) Name of substance Name acc. to inventory CAS No Restriction No Congo red 25g  carcinogenic R28-30 28 Congo red 25g  substances in tattoo inks and permanent make-up R75 75 Congo red 25g azocolourants and azodyes R43 43 Legend R28-30 1. Shall not be placed on the market, or used, – as substances, – as constituents of other substances, or, – in mixtures, for supply to the general public when the individual concentration in the substance or mixture is equal to or greater than: – either the relevant specific concentration limit specified in Part 3 of Annex VI to Regulation (EC) No 1272/2008, or, – the relevant concentration specified in Directive 1999/45/EC where no specific concentration limit is set out in Part 3 of Annex VI to Regulation (EC) No 1272/2008. Without prejudice to the implementation of other Community provisions relating to the classification, packaging and labelling of substances and mixtures, suppliers shall ensure before the placing on the market that the packaging of such substances and mixtures is marked visibly, legibly and indelibly as follows: ‘Restricted to professional users’. 2. By way of derogation, paragraph 1 shall not apply to: (a) medicinal or veterinary products as defined by Directive 2001/82/EC and Directive 2001/83/EC; (b) cosmetic products as defined by Directive 76/768/EEC; (c) the following fuels and oil products: – motor fuels which are covered by Directive 98/70/EC, – mineral oil products intended for use as fuel in mobile or fixed combustion plants, – fuels sold in closed systems (e.g. liquid gas bottles); (d) artists’ paints covered by Directive 1999/45/EC; (e) the substances listed in Appendix 11, column 1, for the applications or uses listed in Appendix 11, column 2. Where a date is specified in column 2 of Appendix 11, the derogation shall apply until the said date; (f) devices covered by Regulation (EU) 2017/745. R43 1. Azodyes which, by reductive cleavage of one or more azo groups, may release one or more of the aromatic amines listed in Appendix 8, in detectable concentrations, i.e. above 30 mg/kg (0,003 % by weight) in the articles or in the dyed parts thereof, according to the testing methods listed in Appendix 10, shall not be used, in textile and leather articles which may come into direct and prolonged contact with the human skin or oral cavity, such as: – clothing, bedding, towels, hairpieces, wigs, hats, nappies and other sanitary items, sleeping bags, – footwear, gloves, wristwatch straps, handbags, purses/wallets, briefcases, chair covers, purses worn round the neck, – textile or leather toys and toys which include textile or leather garments, – yarn and fabrics intended for use by the final consumer. 2. Furthermore, the textile and leather articles referred to in paragraph 1 shall not be placed on the market unless they conform to the requirements set out in that paragraph. 3. Azodyes, which are contained in Appendix 9, ‘List of azodyes’ shall not be placed on the market, or used, as substances, or in mixtures in concentrations greater than 0,1 % by weight, where the substance or the mixture is intended for colouring textile and leather articles. Safety data sheet Legend R75 1. Shall not be placed on the market in mixtures for use for tattooing purposes, and mixtures containing any such substances shall not be used for tattooing purposes, after 4 January 2022 if the substance or substances in question is or are present in the following circumstances: (a) in the case of a substance classified in Part 3 of Annex VI to Regulation (EC) No 1272/2008 as carcinogen category 1A, 1B or 2, or germ cell mutagen category 1A, 1B or 2, the substance is present in the mixture in a concentration equal to or greater than 0,00005 % by weight; (b) in the case of a substance classified in Part 3 of Annex VI to Regulation (EC) No 1272/2008 as reproductive toxicant category 1A, 1B or 2, the substance is present in the mixture in a concentration equal to or greater than 0,001 % by weight; (c) in the case of a substance classified in Part 3 of Annex VI to Regulation (EC) No 1272/2008 as skin sensitiser category 1, 1A or 1B, the substance is present in the mixture in a concentration equal to or greater than 0,001 % by weight; (d) in the case of a substance classified in Part 3 of Annex VI to Regulation (EC) No 1272/2008 as skin corrosive category 1, 1A, 1B or 1C or skin irritant category 2, or as serious eye damage category 1 or eye irritant category 2, the substance is present in the mixture in a concentration equal to or greater than: (i) 0,1 % by weight, if the substance is used solely as a pH regulator; (ii) 0,01 % by weight, in all other cases; (e) in the case of a substance listed in Annex II to Regulation (EC) No 1223/2009 (*1), the substance is present in the mixture in a concentration equal to or greater than 0,00005 % by weight; (f) in the case of a substance for which a condition of one or more of the following kinds is specified in column g (Product type, Body parts) of the table in Annex IV to Regulation (EC) No 1223/2009, the substance is present in the mixture in a concentration equal to or greater than 0,00005 % by weight: (i) “Rinse-off products”; (ii) “Not to be used in products applied on mucous membranes”; (iii) “Not to be used in eye products”; (g) in the case of a substance for which a condition is specified in column h (Maximum concentration in ready for use preparation) or column i (Other) of the table in Annex IV to Regulation (EC) No 1223/2009, the substance is present in the mixture in a concentration, or in some other way, that does not accord with the condition specified in that column; (h) in the case of a substance listed in Appendix 13 to this Annex, the substance is present in the mixture in a concentration equal to or greater than the concentration limit specified for that substance in that Appendix. 2. For the purposes of this entry use of a mixture “for tattooing purposes” means injection or introduction of the mixture into a person’s skin, mucous membrane or eyeball, by any process or procedure (including procedures commonly referred to as permanent make-up, cosmetic tattooing, micro-blading and micro-pigmentation), with the aim of making a mark or design on his or her body. 3. If a substance not listed in Appendix 13 falls within more than one of points (a) to (g) of paragraph 1, the strictest concentration limit laid down in the points in question shall apply to that substance. If a substance listed in Appendix 13 also falls within one or more of points (a) to (g) of paragraph 1, the concentration limit laid down in point (h) of paragraph 1 shall apply to that substance. 4. By way of derogation, paragraph 1 shall not apply to the following substances until 4 January 2023: (a) Pigment Blue 15:3 (CI 74160, EC No 205-685-1, CAS No 147-14-8); (b) Pigment Green 7 (CI 74260, EC No 215-524-7, CAS No 1328-53-6). 5. If Part 3 of Annex VI to Regulation (EC) No 1272/2008 is amended after 4 January 2021 to classify or re-classify a substance such that the substance then becomes caught by point (a), (b), (c) or (d) of paragraph 1 of this entry, or such that it then falls within a different one of those points from the one within which it fell previously, and the date of application of that new or revised classification is after the date referred to in paragraph 1 or, as the case may be, paragraph 4 of this entry, that amendment shall, for the purposes of applying this entry to that substance, be treated as taking effect on the date of application of that new or revised classification. 6. If Annex II or Annex IV to Regulation (EC) No 1223/2009 is amended after 4 January 2021 to list or change the listing of a substance such that the substance then becomes caught by point (e), (f) or (g) of paragraph 1 of this entry, or such that it then falls within a different one of those points from the one within which it fell previously, and the amendment takes effect after the date referred to in paragraph 1 or, as the case may be, paragraph 4 of this entry, that amendment shall, for the purposes of applying this entry to that substance, be treated as taking effect from the date falling 18 months after entry into force of the act by which that amendment was made. 7. Suppliers placing a mixture on the market for use for tattooing purposes shall ensure that, after 4 January 2022, the mixture is marked with the following information: (a) the statement “Mixture for use in tattoos or permanent make-up”; (b) a reference number to uniquely identify the batch; (c) the list of ingredients in accordance with the nomenclature established in the glossary of common ingredient names pursuant to Article 33 of Regulation (EC) No 1223/2009, or in the absence of a common ingredient name, the IUPAC name. In the absence of a common ingredient name or IUPAC name, the CAS and EC number. Ingredients shall be listed in descending order by weight or volume of the ingredients at the time of formulation. “Ingredient” means any substance added during the process of formulation and present in the mixture for use for tattooing purposes. Impurities shall not be regarded as ingredients. If the name of a substance, used as ingredient within the meaning of this entry, is already required to be stated on the label in accordance with Regulation (EC) No 1272/2008, that ingredient does not need to be marked in accordance with this Regulation; (d) the additional statement “pH regulator” for substances falling under point (d)(i) of paragraph 1; (e) the statement “Contains nickel. Can cause allergic reactions.” if the mixture contains nickel below the concentration limit specified in Appendix 13; (f) the statement “Contains chromium (VI). Can cause allergic reactions.” if the mixture contains chromium (VI) below the concentration limit specified in Appendix 13; (g) safety instructions for use insofar as they are not already required to be stated on the label by Regulation (EC) No 1272/2008. The information shall be clearly visible, easily legible and marked in a way that is indelible. The information shall be written in the official language(s) of the Member State(s) where the mixture is placed on the market, unless the Member State(s) concerned provide(s) otherwise. Where necessary because of the size of the package, the information listed in the first subparagraph, except for point (a), shall be included instead in the instructions for use. Before using a mixture for tattooing purposes, the person using the mixture shall provide the person undergoing the procedure with the information marked on the package or included in the instructions for use pursuant to this paragraph. 8. Mixtures that do not contain the statement “Mixture for use in tattoos or permanent make-up” shall not be used for tattooing purposes. Safety data sheet Legend 9. This entry does not apply to substances that are gases at temperature of 20 °C and pressure of 101,3 kPa, or generate a vapour pressure of more than 300 kPa at temperature of 50 °C, with the exception of formaldehyde (CAS No 50- 00-0, EC No 200-001-8). 10. This entry does not apply to the placing on the market of a mixture for use for tattooing purposes, or to the use of a mixture for tattooing purposes, when placed on the market exclusively as a medical device or an accessory to a medical device, within the meaning of Regulation (EU) 2017/745, or when used exclusively as a medical device or an accessory to a medical device, within the same meaning. Where the placing on the market or use may not be exclusively as a medical device or an accessory to a medical device, the requirements of Regulation (EU) 2017/745 and of this Regulation shall apply cumulatively. List of substances subject to authorisation (REACH, Annex XIV)/SVHC – candidate list Substance of Very High Concern (SVHC) Name acc. to inventory CAS No Listed in Remarks Latest application date Sunset date Date of inclusion disodium 3,3′-[[1,1′-biphenyl]- 4,4′-diylbis(azo)]bis(4- aminonaphthalene-1-sulfonate) (C.I. Direct Red 28) 573-58-0 Candidate list Carc. A57a 2013-12-16 Legend candidate list Substances meeting the criteria referred to in Article 57 and for eventual inclusion in Annex XIV Carc. A57a Carcinogenic (article 57a) Seveso Directive 2012/18/EU (Seveso III) No Dangerous substance/hazard categories Qualifying quantity (tonnes) for the application of lower and upper-tier requirements Notes not assigned Deco-Paint Directive VOC content 0 % Industrial Emissions Directive (IED) VOC content 0 % Directive on the restriction of the use of certain hazardous substances in electrical and electronic equipment (RoHS) not listed Regulation concerning the establishment of a European Pollutant Release and Transfer Register (PRTR) not listed Water Framework Directive (WFD) List of pollutants (WFD) Name of substance Name acc. to inventory CAS No Listed in Remarks Congo red Substances and preparations, or the breakdown products of such, which have been proved to possess carcinogenic or mutagenic properties or properties which a) Safety data sheet according to Regulation (EC) No. 1907/2006 (REACH) Congo red (C.I. 22120) for microscopy article number: 0322 United Kingdom (en) Page 13 / 16 List of pollutants (WFD) Name of substance Name acc. to inventory CAS No Listed in Remarks may affect steroidogenic, thyroid, reproduction or other endocrinerelated functions in or via the aquatic environment Congo red Metals and their compounds a) Legend A) Indicative list of the main pollutants Regulation on the marketing and use of explosives precursors not listed Regulation on drug precursors not listed Regulation on substances that deplete the ozone layer (ODS) not listed Regulation concerning the export and import of hazardous chemicals (PIC) chemicals subject to the international prior informed consent (PIC) procedure (the ‘PIC procedure’). Name of substance Name acc. to inventory CAS No Category / subcategory Use limitation Congo red benzidine, salts i(1) i(2) sr b Congo red benzidine, salts i sr Legend b Use limitation: ban (for the sub-category or sub-categories concerned) according to Union legislation i Category: i – industrial chemical i(1) Sub-category: i(1) – industrial chemical for professional use i(2) Sub-category: i(2) – industrial chemical for public use sr Use limitation: severe restriction (for the sub-category or sub-categories concerned) according to Union legislation Regulation on persistent organic pollutants (POP) not listed Other information Directive 94/33/EC on the protection of young people at work. Observe employment restrictions under the Maternity Protection Directive (92/85/EEC) for expectant or nursing mothers. National inventories Country Inventory Status AU AICS substance is listed CA DSL substance is listed CN IECSC substance is listed EU ECSI substance is listed KR KECI substance is listed NZ NZIoC substance is listed PH PICCS substance is listed Safety data sheet United Kingdom (en) Page 14 / 16 Country Inventory Status TW TCSI substance is listed US TSCA substance is listed Legend AICS Australian Inventory of Chemical Substances DSL Domestic Substances List (DSL) ECSI EC Substance Inventory (EINECS, ELINCS, NLP) IECSC Inventory of Existing Chemical Substances Produced or Imported in China KECI Korea Existing Chemicals Inventory NZIoC New Zealand Inventory of Chemicals PICCS Philippine Inventory of Chemicals and Chemical Substances (PICCS) TCSI Taiwan Chemical Substance Inventory TSCA Toxic Substance Control Act 15.2 Chemical Safety Assessment No Chemical Safety Assessment has been carried out for this substance. SECTION 16: Other information Indication of changes (revised safety data sheet) Alignment to regulation: Regulation (EC) No. 1907/2006 (REACH), amended by 2020/878/EU Restructuring: section 9, section 14 Section Former entry (text/value) Actual entry (text/value) Safetyrelevant 2.1 Classification according to Regulation (EC) No 1272/2008 (CLP): change in the listing (table) yes 2.3 Other hazards: There is no additional information. Other hazards yes 2.3 Results of PBT and vPvB assessment: According to the results of its assessment, this substance is not a PBT or a vPvB. yes Abbreviations and acronyms Abbr. Descriptions of used abbreviations ADN Accord européen relatif au transport international des marchandises dangereuses par voies de navigation intérieures (European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways) ADR Accord relatif au transport international des marchandises dangereuses par route (Agreement concerning the International Carriage of Dangerous Goods by Road) Carc. Carcinogenicity CAS Chemical Abstracts Service (service that maintains the most comprehensive list of chemical substances) Ceiling-C Ceiling value CLP Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures DGR Dangerous Goods Regulations (see IATA/DGR) EC No The EC Inventory (EINECS, ELINCS and the NLP-list) is the source for the seven-digit EC number, an identifier of substances commercially available within the EU (European Union) EH40/2005 EH40/2005 Workplace exposure limits (http://www.nationalarchives.gov.uk/doc/open-government-licence/) Safety data sheet United Kingdom (en) Page 15 / 16 Abbr. Descriptions of used abbreviations EINECS European Inventory of Existing Commercial Chemical Substances ELINCS European List of Notified Chemical Substances GHS “Globally Harmonized System of Classification and Labelling of Chemicals” developed by the United Nations IATA International Air Transport Association IATA/DGR Dangerous Goods Regulations (DGR) for the air transport (IATA) ICAO International Civil Aviation Organization IMDG International Maritime Dangerous Goods Code index No The Index number is the identification code given to the substance in Part 3 of Annex VI to Regulation (EC) No 1272/2008 LC50 Lethal Concentration 50%: the LC50 corresponds to the concentration of a tested substance causing 50 % lethality during a specified time interval LD50 Lethal Dose 50 %: the LD50 corresponds to the dose of a tested substance causing 50 % lethality during a specified time interval NLP No-Longer Polymer PBT Persistent, Bioaccumulative and Toxic REACH Registration, Evaluation, Authorisation and Restriction of Chemicals RID Règlement concernant le transport International ferroviaire des marchandises Dangereuses (Regulations concerning the International carriage of Dangerous goods by Rail) STEL Short-term exposure limit SVHC Substance of Very High Concern TWA Time-weighted average VOC Volatile Organic Compounds vPvB Very Persistent and very Bioaccumulative WEL Workplace exposure limit Code Text H350 May cause cancer. H361d Suspected of damaging the unborn child. Safety data sheet