Methylene Blue – Identification of Product Chemical Code: M6450 Chemical Name: Methylene Blue Chemical Grade: ACS Reagent Chemical Formula: C₁₆H₁₈ClN₃S.xH₂O Chemical Weight: 319,85 g/mol CAS No: 122965-43-9 Chemical Synonyms: Tetramethylthionine Chloride, 3,7-bis(Dimethylamino)Phenazathionium Chloride, Basic Blue 9 Methylene Blue – Hazards Identification REACH No: No Data Available Signal Word: Warning Supplemental Hazard Information: Additional Hazard Information: This substance contains no components considered to be either persistent, bio-accumulative and toxic (PBT), or very persistent and very bio-accumulative (vPvB) at levels of 0.1% or higher. Methylene Blue – Hazards statements H302 – Harmful if swallowed. Methylene Blue – Precautionary statements P264 – Wash skin thoroughly after handling. P270 – Do not eat, drink or smoke when using this product. P301 P312 – IF SWALLOWED: Call a POISON CENTER/ doctor if you feel unwell. P501 – Dispose of contents/ container to an approved waste disposal plant. Methylene Blue – Composition of Chemical Chemical Formula: C₁₆H₁₈ClN₃S.xH₂O EC No 1272/2008: No Data Available Methylene Blue – First Aid Measures General Advice: Consult a physician. Show this safety data sheet to the doctor in attendance. If: Inhaled: Move person into fresh air. If not breathing, give artificial respiration. Consult a physician. If: Skin Contact: Wash off with soap and plenty of water. Consult a physician. If: Eye Contac: Flush eyes with water as a precaution. If: Swallowed: Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. Important Symptoms: The most important known symptoms and effects are described in the labeling section Immediate Medical Attention: No Data Available Methylene Blue – Firefighting Measures Extinguishing Media: Use Water spray, Alcohol-resistant foam, Dry chemical or Carbon Dioxide. Hazards Arising: No Data Available Advice for Firefighters: Wear self-contained breathing apparatus for firefighting if necessary. Info for Firefighting: No Data Available Methylene Blue – Accidental Release Measures Personal Precautions: Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Avoid breathing dust. Environmental Precautions: Do not let product enter drains. Method for Containment: Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal. Methylene Blue – Handling and Storage Personal Precautions: Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed. Environmental Precautions: Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Exposure Controls | Personal Protection Derived No Effect Level (DNEL) Workers | Application Area | Exposure Routes | Health Effect | Value No Data Available Consumers | Application Area | Exposure Routes | Health Effect | Value No Data Available Predicted No Effect Concentration (PNEC) No Data Available Engineering Controls: Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Eye/Face Protection: Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin Protection: Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching gloves outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Full contact – Material: Nitrile rubber. Minimum layer thickness: 0,11 mm Break through time: 480 min. Material tested: Dermatril® Splash contact – Material: Nitrile rubber. Minimum layer thickness: 0,11 mm Break through time: 480 min. Material tested: Dermatril® Data source: KCL GmbH, D-36124. Test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection: Complete suit protecting against chemicals. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Respiratory Protection: For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle respirator. For higher level protection use type OV/AG/P99 (US) or type ABEK-P2 (EU EN 143) respirator cartridges. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Physical and Chemical Properties Appearance: Dark Green Crystals with Bronze lustre, or Crystalline Powder Odour: Odourless Odour Threshold: No Data Available pH: No Data Available Melting Point: No Data Available Boiling Point: No Data Available Flash Point: No Data Available Evaporation: No Data Available Flammability: No Data Available Upper/Lower Flammability or Explosive Limits: No Data Available Vapour pressure: No Data Available Vapour density: No Data Available Relative density: No Data Available Water solubility: Soluble Partition Coefficien: No Data Available Auto-ignition Temperature: No Data Available Decomposition Temperature: No Data Available Viscosity: No Data Available Explosive properties: No Data Available Oxidizing properties: No Data Available Other Safety Info: No Data Available Stability and Reactivity Reactivity: No Data Available Chemical Stability: Stable under recommended storage conditions. Possibility of hazardous reactions: No Data Available Conditions to Avoid: No Data Available Incompatible Materials: Strong Oxidizing Agents Hazardous Decomposition Products: Hazardous decomposition products formed under fire conditions – Carbon Oxides, Nitrogen Oxides, Sulphur Oxides, Hydrogen Chloride gas Toxicological Information Acute Toxicity: No Data Available Skin Corrosion/Irritation: No Data Available Serious Eye damage | Eye Irritation: No Data Available Cell Mutagenicity: No Data Available Carcinogenicity: IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC. Reproductive toxicity: No Data Available Specific Target Organ Toxicity – Single Exposure: No Data Available Specific Target Organ Toxicity – Repeated Exposure: No Data Available Aspiration Hazard: No Data Available Ecological Information Ecological Toxicity: No Data Available Ecological Persistence and degradability: No Data Available Bio-accumulative Potential: No Data Available Mobility in Soil: No Data Available Results of PBT and vPvB Assessment: This substance contains no components considered to be either persistent, bio-accumulative and toxic (PBT), or very persistent and very bio-accumulative (vPvB) at levels of 0.1% or higher. Other Adverse Effect: No Data Available Disposal Considerations Waste Treatment Methods: Product – Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Contaminated packaging – Dispose of as unused product. Transport Information UN Number: ADR/RID: – IMDG: – IATA: – UN Shipping Hazard: ADR/RID: Not dangerous goods IMDG: Not dangerous goods IATA: Not dangerous goods Transport Hazard Class: ADR/RID: – IMDG: – IATA: – Packaging Group: ADR/RID: – IMDG: – IATA: – Environmental Hazards: ADR/RID: no IMDG Marine pollutant: no IATA: no Special Precautions: No data available Regulatory Information Safety, Health and environmental regulations: This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006. Chemical Safety Assessment: For this product a chemical safety assessment was not carried out. Additional Info: RTECS: SP5740000 Absorption into the body leads to the formation of Methemoglobin which in sufficient concentration causes Cyanosis. Onset may be delayed 2 to 4 hours or longer. Vomiting, Diarrhoea, Nausea, Dizziness, Headache Disclaimer The information stated above is considered to be correct, but does not claim to be inclusive and shall only be used as a guideline. The information provided by this document is confirmed by our continuous updating of knowledge and adheres to the products appropriate safety precautions. It does not represent any guarantee of the product’s properties. RLS Chemicals and its Associates shall not be held accountable for any damage’s consequent of handling the above product.
